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Phenotypic characterization of single CD4+ T cells harboring genetically intact and inducible HIV genomes

The phenotype of the rare HIV-infected cells persisting during antiretroviral therapies (ART) remains elusive. We developed a single-cell approach that combines the phenotypic analysis of HIV-infected cells with near full-length sequencing of their associated proviruses to characterize the viral res...

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Detalles Bibliográficos
Autores principales: Dufour, Caroline, Richard, Corentin, Pardons, Marion, Massanella, Marta, Ackaoui, Antoine, Murrell, Ben, Routy, Bertrand, Thomas, Réjean, Routy, Jean-Pierre, Fromentin, Rémi, Chomont, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971253/
https://www.ncbi.nlm.nih.gov/pubmed/36849523
http://dx.doi.org/10.1038/s41467-023-36772-x