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N-glycolylneuraminic acid as a carbohydrate cancer biomarker

One of the forms of aberrant glycosylation in human tumors is the expression of N-glycolylneuraminic acid (Neu5Gc). The only known enzyme to biosynthesize Neu5Gc in mammals, cytidine-5′-monophosphate-N-acetylneuraminic acid (CMAH), appears to be genetically inactivated in humans. Regardless, low lev...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Shewell, Lucy K., Day, Christopher J., Jennings, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971276/
https://www.ncbi.nlm.nih.gov/pubmed/36805917
http://dx.doi.org/10.1016/j.tranon.2023.101643