E3 ligase adaptor FBXO7 contributes to ubiquitination and proteasomal degradation of SIRT7 and promotes cell death in response to hydrogen peroxide

Parkinson’s disease (PD) is a degenerative disorder of the central nervous system that affects 1% of the population over the age of 60. Although aging is one of the main risk factors for PD, the pathogenic mechanism of this disease remains unclear. Mutations in the F-box-only protein 7 (FBXO7) gene...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Su Hyoun, Lee, Yun Ju, Jung, Sungyeon, Chung, Kwang Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971319/
https://www.ncbi.nlm.nih.gov/pubmed/36646384
http://dx.doi.org/10.1016/j.jbc.2023.102909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971319/
https://www.ncbi.nlm.nih.gov/pubmed/36646384
http://dx.doi.org/10.1016/j.jbc.2023.102909

Ejemplares similares