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Microsatellite instability assessment is instrumental for Predictive, Preventive and Personalised Medicine: status quo and outlook
A form of genomic alteration called microsatellite instability (MSI) occurs in a class of tandem repeats (TRs) called microsatellites (MSs) or short tandem repeats (STRs) due to the failure of a post-replicative DNA mismatch repair (MMR) system. Traditionally, the strategies for determining MSI even...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971410/ https://www.ncbi.nlm.nih.gov/pubmed/36866160 http://dx.doi.org/10.1007/s13167-023-00312-w |