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Clinical Implication of DNMT3A and TET2 Genes Mutations in Cytogenetically Normal Acute Myeloid Leukemia

BACKGROUND: Refining risk stratification of cytogenetically normal AML (CN-AML) cases is important for decision making and tailoring of therapy. In this context genetic and epigenetic mutations was considered. Among these epigenetic regulators are DNMT3A & TET2 genes. Therefore, the aim of this...

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Detalles Bibliográficos
Autores principales: Aref, Salah, Sallam, Nahed, Abd Elaziz, Sherin, Salama, Osama, Al Ashwah, Shaimaa, Ayed, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971478/
https://www.ncbi.nlm.nih.gov/pubmed/36580013
http://dx.doi.org/10.31557/APJCP.2022.23.12.4299