A human antibody potently neutralizes RSV by targeting the conserved hydrophobic region of prefusion F

Respiratory syncytial virus (RSV) continues to pose serious threats to pediatric populations due to the lack of a vaccine and effective antiviral drugs. RSV fusion (F) glycoprotein mediates viral-host membrane fusion and is a key target for neutralizing antibodies. We generated 23 full-human monoclo...

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Detalles Bibliográficos
Autores principales: Yi, Chunyan, Su, Caixia, Sun, Xiaoyu, Lu, Xiao, Si, Chuanya, Liu, Caixuan, Yang, Zhuo, Yuan, Hong, Huang, Yuying, Wen, Jing, He, Yonghui, Zhang, Yaguang, Ma, Liyan, Cong, Yao, Zhao, Gan, Ling, Zhiyang, Wang, Bin, Sun, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science China Press 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971687/
https://www.ncbi.nlm.nih.gov/pubmed/36853487
http://dx.doi.org/10.1007/s11427-022-2250-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971687/
https://www.ncbi.nlm.nih.gov/pubmed/36853487
http://dx.doi.org/10.1007/s11427-022-2250-0

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