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The skeletal muscle phenotype of the DE50-MD dog model of Duchenne muscular dystrophy

Background: Animal models of Duchenne muscular dystrophy (DMD) are essential to study disease progression and assess efficacy of therapeutic intervention, however dystrophic mice fail to display a clinically relevant phenotype, limiting translational utility. Dystrophin-deficient dogs exhibit diseas...

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Detalles Bibliográficos
Autores principales: Hildyard, John C.W., Riddell, Dominique O., Harron, Rachel C.M., Rawson, Faye, Foster, Emma M.A., Massey, Claire, Taylor-Brown, Frances, Wells, Dominic J., Piercy, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971692/
https://www.ncbi.nlm.nih.gov/pubmed/36865375
http://dx.doi.org/10.12688/wellcomeopenres.18251.1