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In silico Identification of Hypoxic Signature followed by reverse transcription-quantitative PCR Validation in Cancer Cell Lines

BACKGROUND: Hypoxic tumor microenvironment is one of the important impediments for conventional cancer therapy. This study aimed to computationally identify hypoxia-related mRNA signatures in nine hypoxic-conditioned cancer cell lines and investigate their role during hypoxia. METHODS: Nine RNA-Seq...

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Detalles Bibliográficos
Autores principales: Shayan, Sara, Bahramali, Golnaz, Arashkia, Arash, Azadmanesh, Kayhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971715/
https://www.ncbi.nlm.nih.gov/pubmed/36624663
http://dx.doi.org/10.52547/ibj.3803