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High-speed 2D light-sheet fluorescence microscopy enables quantification of spatially varying calcium dynamics in ventricular cardiomyocytes

Introduction: Reduced synchrony of calcium release and t-tubule structure organization in individual cardiomyocytes has been linked to loss of contractile strength and arrhythmia. Compared to confocal scanning techniques widely used for imaging calcium dynamics in cardiac muscle cells, light-sheet f...

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Detalles Bibliográficos
Autores principales: Dvinskikh, Liuba, Sparks, Hugh, MacLeod, Kenneth T., Dunsby, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971815/
https://www.ncbi.nlm.nih.gov/pubmed/36866170
http://dx.doi.org/10.3389/fphys.2023.1079727