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Pluripotency retention and exogenous mRNA introduction in planarian stem cells in culture

Planarians possess naturally occurring pluripotent adult somatic stem cells (neoblasts) required for homeostasis and whole-body regeneration. However, no reliable neoblast culture methods are currently available, hindering mechanistic studies of pluripotency and the development of transgenic tools....

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Detalles Bibliográficos
Autores principales: Lei, Kai, Zhang, Wenya, Chen, Jiajia, McKinney, Sean A., Ross, Eric J., Lee, Heng-Chi, Sánchez Alvarado, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971864/
https://www.ncbi.nlm.nih.gov/pubmed/36866042
http://dx.doi.org/10.1016/j.isci.2023.106001