An RNA stem-loop functions in conjunction with an upstream open reading frame to direct preferential translation in the integrated stress response

In response to environmental stresses, cells invoke translational control to conserve resources and rapidly reprogram gene expression for optimal adaptation. A central mechanism for translational control involves phosphorylation of the α subunit of eIF2 (p-eIF2α), which reduces delivery of initiator...

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Detalles Bibliográficos
Autores principales: Amin, Parth H., Carlson, Kenneth R., Wek, Ronald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971878/
https://www.ncbi.nlm.nih.gov/pubmed/36596357
http://dx.doi.org/10.1016/j.jbc.2022.102864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971878/
https://www.ncbi.nlm.nih.gov/pubmed/36596357
http://dx.doi.org/10.1016/j.jbc.2022.102864

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