White matter hyperintensities in cholinergic pathways are associated with dementia severity in e4 carriers but not in non-carriers

BACKGROUND AND OBJECTIVES: Among individuals with Alzheimer's disease (AD), APOE e4 carriers with increased white matter hyperintensities (WMHs) may selectively be at increased risk of cognitive impairment. Given that the cholinergic system plays a crucial role in cognitive impairment, this stu...

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Detalles Bibliográficos
Autores principales: Yu, Ming-Chun, Chuang, Yi-Fang, Wu, Shu-Ching, Ho, Cheng-Feng, Liu, Yi-Chien, Chou, Chia-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971995/
https://www.ncbi.nlm.nih.gov/pubmed/36864910
http://dx.doi.org/10.3389/fneur.2023.1100322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971995/
https://www.ncbi.nlm.nih.gov/pubmed/36864910
http://dx.doi.org/10.3389/fneur.2023.1100322

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