Ocular protein optineurin shows reversibility from unfolded states and exhibits chaperone-like activity

Optineurin (OPTN) is a multifunctional, ubiquitously expressed cytoplasmic protein, mutants of which are associated with primary open-angle glaucoma (POAG) and amyotrophic lateral sclerosis (ALS). The most abundant heat shock protein crystallin, known for its remarkable thermodynamic stability and c...

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Detalles Bibliográficos
Autores principales: Dixit, Anjali, Chakraborty, Ankan, Nath, Jyoti Rani, Chowdhury, Pramit K., Kundu, Bishwajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972007/
https://www.ncbi.nlm.nih.gov/pubmed/36865578
http://dx.doi.org/10.1039/d2ra07931c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972007/
https://www.ncbi.nlm.nih.gov/pubmed/36865578
http://dx.doi.org/10.1039/d2ra07931c

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