A phase I trial of metformin in combination with vincristine, irinotecan, and temozolomide in children with relapsed or refractory solid and central nervous system tumors: A report from the national pediatric cancer foundation

BACKGROUND: Patients with relapsed and refractory solid and central nervous system (CNS) tumors have poor outcomes and need novel therapeutic options. Vincristine, irinotecan, and temozolomide (VIT) is a common chemotherapy regimen in relapsed pediatric tumors with an established toxicity profile. M...

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Detalles Bibliográficos
Autores principales: Metts, Jonathan L., Trucco, Matteo, Weiser, Daniel A., Thompson, Patrick, Sandler, Eric, Smith, Tiffany, Crimella, Jessica, Sansil, Samer, Thapa, Ram, Fridley, Brooke L., Llosa, Nicholas, Badgett, Thomas, Gorlick, Richard, Reed, Damon, Gill, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972017/
https://www.ncbi.nlm.nih.gov/pubmed/36151773
http://dx.doi.org/10.1002/cam4.5297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972017/
https://www.ncbi.nlm.nih.gov/pubmed/36151773
http://dx.doi.org/10.1002/cam4.5297

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