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Systemic analysis of the DNA replication regulator origin recognition complex in lung adenocarcinomas identifies prognostic and expression significance

BACKGROUND: DNA replication alteration is a hallmark of patients with lung adenocarcinoma (LUAD) and is frequently observed in LUAD progression. Origin recognition complex (ORC) 1, ORC2, ORC3, ORC4, ORC5, and ORC6 form a replication–initiator complex to mediate DNA replication, which plays a key rol...

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Detalles Bibliográficos
Autores principales: Tang, Min, Chen, Juan, Zeng, Tian, Ye, Dong‐mei, Li, Yu‐kun, Zou, Juan, Zhang, Yu‐ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972100/
https://www.ncbi.nlm.nih.gov/pubmed/36205357
http://dx.doi.org/10.1002/cam4.5238