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Integration of Candida albicans-induced single-cell gene expression data and secretory protein concentrations reveal genetic regulators of inflammation

Both gene expression and protein concentrations are regulated by genetic variants. Exploring the regulation of both eQTLs and pQTLs simultaneously in a context- and cell-type dependent manner may help to unravel mechanistic basis for genetic regulation of pQTLs. Here, we performed meta-analysis of C...

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Detalles Bibliográficos
Autores principales: Boahen, Collins K., Oelen, Roy, Le, Kieu, Netea, Mihai G., Franke, Lude, van der Wijst, Monique G.P., Kumar, Vinod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972217/
https://www.ncbi.nlm.nih.gov/pubmed/36865558
http://dx.doi.org/10.3389/fimmu.2023.1069379