Cargando…
Zika virus RNA structure controls its unique neurotropism by bipartite binding to Musashi-1
Human RNA binding protein Musashi-1 (MSI1) plays a critical role in neural progenitor cells (NPCs) by binding to various host RNA transcripts. The canonical MSI1 binding site (MBS), A/GU((1-3))AG single-strand motif, is present in many RNA virus genomes, but only Zika virus (ZIKV) genome has been de...
Autores principales: | Chen, Xiang, Wang, Yan, Xu, Zhonghe, Cheng, Meng-Li, Ma, Qing-Qing, Li, Rui-Ting, Wang, Zheng-Jian, Zhao, Hui, Zuo, Xiaobing, Li, Xiao-Feng, Fang, Xianyang, Qin, Cheng-Feng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972320/ https://www.ncbi.nlm.nih.gov/pubmed/36854751 http://dx.doi.org/10.1038/s41467-023-36838-w |
Ejemplares similares
-
Visualization of a neurotropic flavivirus infection in mouse reveals unique viscerotropism controlled by host type I interferon signaling
por: Li, Xiao-Feng, et al.
Publicado: (2017) -
Musashi binding elements in Zika and related Flavivirus 3′UTRs: A comparative study in silico
por: Schneider, Adriano de Bernardi, et al.
Publicado: (2019) -
Neurotropism and behavioral changes associated with Zika infection in the vector Aedes aegypti
por: Gaburro, Julie, et al.
Publicado: (2018) -
Inhibition of RNA-Binding Protein Musashi-1 Suppresses Malignant Properties and Reverses Paclitaxel Resistance in Ovarian Carcinoma
por: Chen, Huaizeng, et al.
Publicado: (2019) -
Tau oligomers mediate aggregation of RNA‐binding proteins Musashi1 and Musashi2 inducing Lamin alteration
por: Montalbano, Mauro, et al.
Publicado: (2019)