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Targeting circulating high mobility group box-1 and histones by extracorporeal blood purification as an immunomodulation strategy against critical illnesses

Both high mobility group box-1 (HMGB1) and histones are major damage-associated molecular patterns (DAPMs) that mediate lethal systemic inflammation, activation of the complement and coagulation system, endothelial injury and multiple organ dysfunction syndrome in critical illnesses. Although accumu...

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Detalles Bibliográficos
Autores principales: Li, Yupei, Chen, Yu, Yang, Tinghang, Chang, Kaixi, Deng, Ningyue, Zhao, Weifeng, Su, Baihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972334/
https://www.ncbi.nlm.nih.gov/pubmed/36855150
http://dx.doi.org/10.1186/s13054-023-04382-0