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Neurofilament light oligomers in neurodegenerative diseases: quantification by homogeneous immunoassay in cerebrospinal fluid

BACKGROUND: Neurofilament light (NfL) is a widely used biomarker for neurodegeneration. NfL is prone to oligomerisation, but available assays do not reveal the exact molecular nature of the protein variant measured. The objective of this study was to develop a homogeneous ELISA capable of quantifyin...

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Detalles Bibliográficos
Autores principales: Meda, Francisco J., Knowles, Kathryn, Swift, Imogen J., Sogorb-Esteve, Aitana, Rohrer, Jonathan D., Dittrich, Anna, Skoog, Ingmar, Kern, Silke, Becker, Bruno, Blennow, Kaj, Andreasson, Ulf, Kvartsberg, Hlin, Zetterberg, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972422/
https://www.ncbi.nlm.nih.gov/pubmed/36865081
http://dx.doi.org/10.1136/bmjno-2022-000395