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Neurofilament light oligomers in neurodegenerative diseases: quantification by homogeneous immunoassay in cerebrospinal fluid
BACKGROUND: Neurofilament light (NfL) is a widely used biomarker for neurodegeneration. NfL is prone to oligomerisation, but available assays do not reveal the exact molecular nature of the protein variant measured. The objective of this study was to develop a homogeneous ELISA capable of quantifyin...
Autores principales: | Meda, Francisco J., Knowles, Kathryn, Swift, Imogen J., Sogorb-Esteve, Aitana, Rohrer, Jonathan D., Dittrich, Anna, Skoog, Ingmar, Kern, Silke, Becker, Bruno, Blennow, Kaj, Andreasson, Ulf, Kvartsberg, Hlin, Zetterberg, Henrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972422/ https://www.ncbi.nlm.nih.gov/pubmed/36865081 http://dx.doi.org/10.1136/bmjno-2022-000395 |
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