Synthesis of Quinoline and Dihydroquinoline Embelin Derivatives as Cardioprotective Agents

[Image: see text] A set of new dihydroquinoline embelin derivatives was obtained from the reaction of the natural benzoquinone embelin (1) with anilines and aromatic aldehydes in the presence of AgOTf. The synthesis of these compounds involves the formation of a Knoevenagel adduct, followed by nucle...

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Detalles Bibliográficos
Autores principales: Martín-Acosta, Pedro, Cuadrado, Irene, González-Cofrade, Laura, Pestano, Roberto, Hortelano, Sonsoles, de las Heras, Beatriz, Estévez-Braun, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972480/
https://www.ncbi.nlm.nih.gov/pubmed/36749898
http://dx.doi.org/10.1021/acs.jnatprod.2c00924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972480/
https://www.ncbi.nlm.nih.gov/pubmed/36749898
http://dx.doi.org/10.1021/acs.jnatprod.2c00924

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