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Synthesis of Quinoline and Dihydroquinoline Embelin Derivatives as Cardioprotective Agents
[Image: see text] A set of new dihydroquinoline embelin derivatives was obtained from the reaction of the natural benzoquinone embelin (1) with anilines and aromatic aldehydes in the presence of AgOTf. The synthesis of these compounds involves the formation of a Knoevenagel adduct, followed by nucle...
Autores principales: | Martín-Acosta, Pedro, Cuadrado, Irene, González-Cofrade, Laura, Pestano, Roberto, Hortelano, Sonsoles, de las Heras, Beatriz, Estévez-Braun, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society and American Society of Pharmacognosy
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972480/ https://www.ncbi.nlm.nih.gov/pubmed/36749898 http://dx.doi.org/10.1021/acs.jnatprod.2c00924 |
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