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Elevated serum levels of glial fibrillary acidic protein are associated with covert hepatic encephalopathy in patients with cirrhosis

BACKGROUND & AIMS: Blood biomarkers facilitating the diagnosis of covert hepatic encephalopathy (CHE) in patients with cirrhosis are lacking. Astrocyte swelling is a major component of hepatic encephalopathy. Thus, we hypothesised that glial fibrillary acidic protein (GFAP), the major intermedia...

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Detalles Bibliográficos
Autores principales: Gairing, Simon Johannes, Danneberg, Sven, Kaps, Leonard, Nagel, Michael, Schleicher, Eva Maria, Quack, Charlotte, Engel, Sinah, Bittner, Stefan, Galle, Peter Robert, Schattenberg, Jörn Markus, Wörns, Marcus-Alexander, Luessi, Felix, Marquardt, Jens Uwe, Labenz, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972561/
https://www.ncbi.nlm.nih.gov/pubmed/36866390
http://dx.doi.org/10.1016/j.jhepr.2023.100671