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Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic Mice

BACKGROUND & AIMS: Observational epidemiologic studies have associated vitamin D deficiency with cholestasis. We reported previously that activation of the vitamin D/vitamin D receptor (VDR) axis in cholangiocytes mitigates cholestatic liver injury by remodeling the damaged bile duct. However, t...

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Detalles Bibliográficos
Autores principales: Zheng, Zhijian, Xie, Jing, Ma, Liman, Hao, Zhiqing, Zhang, Weiwei, Li, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972562/
https://www.ncbi.nlm.nih.gov/pubmed/36280140
http://dx.doi.org/10.1016/j.jcmgh.2022.10.011