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Hepatitis B Virus DNA Integration Drives Carcinogenesis and Provides a New Biomarker for HBV-related HCC

Hepatitis B virus (HBV) DNA integration is an incidental event in the virus replication cycle and occurs in less than 1% of infected hepatocytes during viral infection. However, HBV DNA is present in the genome of approximately 90% of HBV-related HCCs and is the most common somatic mutation. Whole g...

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Detalles Bibliográficos
Autores principales: Yeh, Shiou-Hwei, Li, Chiao-Ling, Lin, You-Yu, Ho, Ming-Chih, Wang, Ya-Chun, Tseng, Sheng-Tai, Chen, Pei-Jer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972564/
https://www.ncbi.nlm.nih.gov/pubmed/36690297
http://dx.doi.org/10.1016/j.jcmgh.2023.01.001