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IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps

The nasal polyps (NPs) microenvironment comprises multiple cell types, including mesenchymal stromal cells (MSCs). Insulin-like growth factor binding protein 2 (IGFBP2) plays crucial roles in cell proliferation, differentiation and more. However, the role of NPs-derived MSCs (PO-MSCs) and IGFBP2 in...

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Detalles Bibliográficos
Autores principales: You, Bo, Zhang, Ting, Zhang, Wei, Pei, Yinyin, Huang, Danyi, Lei, Yun, Zhang, Shaocong, Qiu, Changyu, Zhang, Jie, Gu, Zhifeng, Cheng, Lei, Chen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972572/
https://www.ncbi.nlm.nih.gov/pubmed/36866245
http://dx.doi.org/10.1016/j.isci.2023.106151