Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis

BACKGROUND & AIMS: Fibroblast activation protein (FAP) is expressed on activated fibroblast. Its role in fibrosis and desmoplasia is controversial, and data on pharmacological FAP inhibition are lacking. We aimed to better define the role of FAP in liver fibrosis in vivo and in vitro. METHODS: F...

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Detalles Bibliográficos
Autores principales: Yang, Ai-Ting, Kim, Yong-Ook, Yan, Xu-Zhen, Abe, Hiroyuki, Aslam, Misbah, Park, Kyoung-Sook, Zhao, Xin-Yan, Jia, Ji-Dong, Klein, Thomas, You, Hong, Schuppan, Detlef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972574/
https://www.ncbi.nlm.nih.gov/pubmed/36521660
http://dx.doi.org/10.1016/j.jcmgh.2022.12.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972574/
https://www.ncbi.nlm.nih.gov/pubmed/36521660
http://dx.doi.org/10.1016/j.jcmgh.2022.12.005

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