A new intronic quantitative PCR method led to the discovery of transformation from human ascites to murine malignancy in a mouse model

PURPOSE: To establish a fast and accurate detection method for interspecies contaminations in the patient-derived xenograft (PDX) models and cell lines, and to elucidate possible mechanisms if interspecies oncogenic transformation is detected. METHODS: A fast and highly sensitive intronic qPCR metho...

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Detalles Bibliográficos
Autores principales: Jin, Jiankang, Huo, Longfei, Fan, Yibo, Wang, Ruiping, Scott, Ailing W., Pizzi, Melissa Pool, Yao, Xiaodan, Shao, Shan, Ma, Lang, Da Silva, Matheus S., Yamashita, Kohei, Yoshimura, Katsuhiro, Zhang, Boyu, Wu, Jingjing, Wang, Linghua, Song, Shumei, Ajani, Jaffer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972586/
https://www.ncbi.nlm.nih.gov/pubmed/36865791
http://dx.doi.org/10.3389/fonc.2023.1062424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972586/
https://www.ncbi.nlm.nih.gov/pubmed/36865791
http://dx.doi.org/10.3389/fonc.2023.1062424

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