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SIRT2-PFKP interaction dysregulates phagocytosis in macrophages with acute ethanol-exposure

Alcohol abuse, reported by 1/8(th) critically ill patients, is an independent risk factor for death in sepsis. Sepsis kills over 270,000 patients/year in the US. We reported that the ethanol-exposure suppresses innate-immune response, pathogen clearance, and decreases survival in sepsis-mice via sir...

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Detalles Bibliográficos
Autores principales: Gandhirajan, Anugraha, Roychowdhury, Sanjoy, Kibler, Christopher, Cross, Emily, Abraham, Susamma, Bellar, Annett, Nagy, Laura E., Scheraga, Rachel Greenberg, Vachharajani, Vidula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972587/
https://www.ncbi.nlm.nih.gov/pubmed/36865524
http://dx.doi.org/10.3389/fimmu.2022.1079962