CeDAR: incorporating cell type hierarchy improves cell type-specific differential analyses in bulk omics data

Bulk high-throughput omics data contain signals from a mixture of cell types. Recent developments of deconvolution methods facilitate cell type-specific inferences from bulk data. Our real data exploration suggests that differential expression or methylation status is often correlated among cell typ...

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Detalles Bibliográficos
Autores principales: Chen, Luxiao, Li, Ziyi, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972684/
https://www.ncbi.nlm.nih.gov/pubmed/36855165
http://dx.doi.org/10.1186/s13059-023-02857-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972684/
https://www.ncbi.nlm.nih.gov/pubmed/36855165
http://dx.doi.org/10.1186/s13059-023-02857-5

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