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DNA methylation as a potential mediator of the association between indoor air pollution and neurodevelopmental delay in a South African birth cohort

BACKGROUND: Exposure to indoor air pollution during pregnancy has been linked to neurodevelopmental delay in toddlers. Epigenetic modification, particularly DNA methylation (DNAm), may explain this link. In this study, we employed three high-dimensional mediation analysis methods (HIMA, DACT, and gH...

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Detalles Bibliográficos
Autores principales: Feil, Dakotah, Abrishamcar, Sarina, Christensen, Grace M., Vanker, Aneesa, Koen, Nastassja, Kilanowski, Anna, Hoffman, Nadia, Wedderburn, Catherine J., Donald, Kirsten A., Kobor, Michael S., Zar, Heather J., Stein, Dan J., Hüls, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972733/
https://www.ncbi.nlm.nih.gov/pubmed/36855151
http://dx.doi.org/10.1186/s13148-023-01444-6