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Early tau detection in flortaucipir images: validation in autopsy-confirmed data and implications for disease progression

BACKGROUND: There is an increasing interest in utilizing tau PET to identify patients early in Alzheimer’s disease (AD). In this work, a temporal lobe composite (Eτ) volume of interest (VOI) was evaluated in a longitudinal flortaucipir cohort and compared to a previously described global neocortical...

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Detalles Bibliográficos
Autores principales: Kotari, Vikas, Southekal, Sudeepti, Navitsky, Michael, Kennedy, Ian A., Lu, Ming, Morris, Amanda, Zimmer, Jennifer Ann, Fleisher, Adam S., Mintun, Mark A., Devous, Michael D., Pontecorvo, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972744/
https://www.ncbi.nlm.nih.gov/pubmed/36855201
http://dx.doi.org/10.1186/s13195-023-01160-6