Cargando…
Early tau detection in flortaucipir images: validation in autopsy-confirmed data and implications for disease progression
BACKGROUND: There is an increasing interest in utilizing tau PET to identify patients early in Alzheimer’s disease (AD). In this work, a temporal lobe composite (Eτ) volume of interest (VOI) was evaluated in a longitudinal flortaucipir cohort and compared to a previously described global neocortical...
Autores principales: | Kotari, Vikas, Southekal, Sudeepti, Navitsky, Michael, Kennedy, Ian A., Lu, Ming, Morris, Amanda, Zimmer, Jennifer Ann, Fleisher, Adam S., Mintun, Mark A., Devous, Michael D., Pontecorvo, Michael J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972744/ https://www.ncbi.nlm.nih.gov/pubmed/36855201 http://dx.doi.org/10.1186/s13195-023-01160-6 |
Ejemplares similares
-
A multicentre longitudinal study of flortaucipir ((18)F) in normal ageing, mild cognitive impairment and Alzheimer’s disease dementia
por: Pontecorvo, Michael J, et al.
Publicado: (2019) -
Relationships between flortaucipir PET tau binding and amyloid burden, clinical diagnosis, age and cognition
por: Pontecorvo, Michael J., et al.
Publicado: (2017) -
Comparison of regional flortaucipir PET with quantitative tau immunohistochemistry in three subjects with Alzheimer’s disease pathology: a clinicopathological study
por: Pontecorvo, Michael J., et al.
Publicado: (2020) -
Tau as a diagnostic instrument in clinical trials to predict amyloid in Alzheimer's disease
por: Shcherbinin, Sergey, et al.
Publicado: (2023) -
Aggregated Tau Measured by Visual Interpretation of Flortaucipir Positron
Emission Tomography and the Associated Risk of Clinical Progression of Mild Cognitive
Impairment and Alzheimer Disease: Results From 2 Phase III Clinical Trials
por: Lu, Ming, et al.
Publicado: (2021)