Phospholipase C delta 1 inhibits WNT/β‐catenin and EGFR-FAK-ERK signaling and is disrupted by promoter CpG methylation in renal cell carcinoma

BACKGROUND: PLCD1, located at 3p22, encodes an enzyme that mediates cellular metabolism and homeostasis, intracellular signal transduction and movement. PLCD1 plays a pivotal role in tumor suppression of several types of cancers; however, its expression and underlying molecular mechanisms in renal c...

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Detalles Bibliográficos
Autores principales: Xie, Jianlian, Zhou, Jun, Xia, Jiliang, Zeng, Ying, Huang, Guo, Zeng, Weihong, Fan, Tingyu, Li, Lili, Zeng, Xi, Tao, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972803/
https://www.ncbi.nlm.nih.gov/pubmed/36849889
http://dx.doi.org/10.1186/s13148-023-01448-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972803/
https://www.ncbi.nlm.nih.gov/pubmed/36849889
http://dx.doi.org/10.1186/s13148-023-01448-2

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