Immunization of Mice with Virus-Like Vesicles of Kaposi Sarcoma-Associated Herpesvirus Reveals a Role for Antibodies Targeting ORF4 in Activating Complement-Mediated Neutralization

Infection by Kaposi sarcoma-associated herpesvirus (KSHV) can cause severe consequences, such as cancers and lymphoproliferative diseases. Whole inactivated viruses (WIV) with chemically destroyed genetic materials have been used as antigens in several licensed vaccines. During KSHV productive repli...

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Detalles Bibliográficos
Autores principales: Lam, Alex K., Roshan, Romin, Miley, Wendell, Labo, Nazzarena, Zhen, James, Kurland, Andrew P., Cheng, Celine, Huang, Haigen, Teng, Pu-Lin, Harelson, Claire, Gong, Danyang, Tam, Ying K., Radu, Caius G., Epeldegui, Marta, Johnson, Jeffrey R., Zhou, Z. Hong, Whitby, Denise, Wu, Ting-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972917/
https://www.ncbi.nlm.nih.gov/pubmed/36757205
http://dx.doi.org/10.1128/jvi.01600-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972917/
https://www.ncbi.nlm.nih.gov/pubmed/36757205
http://dx.doi.org/10.1128/jvi.01600-22

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