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Trimeric, APC-Targeted Subunit Vaccines Protect Mice against Seasonal and Pandemic Influenza

Viral subunit vaccines contain the specific antigen deemed most important for development of protective immune responses. Typically, the chosen antigen is a surface protein involved in cellular entry of the virus, and neutralizing antibodies may prevent this. For influenza, hemagglutinin (HA) is thu...

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Detalles Bibliográficos
Autores principales: Tjärnhage, Elias, Brown, Diamond, Bogen, Bjarne, Andersen, Tor Kristian, Grødeland, Gunnveig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972960/
https://www.ncbi.nlm.nih.gov/pubmed/36719241
http://dx.doi.org/10.1128/jvi.01694-22