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The immunoregulatory effect of the TREM2-agonist Sulfavant A in human allogeneic mixed lymphocyte reaction

INTRODUCTION: Sulfavant A (SULF A) is a synthetic derivative of naturally occurring sulfolipids. The molecule triggers TREM2-related maturation of dendritic cells (DCs) and has shown promising adjuvant activity in a cancer vaccine model. METHODS: the immunomodulatory activity of SULF A is tested in...

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Detalles Bibliográficos
Autores principales: Barra, Giusi, Gallo, Carmela, Carbone, Dalila, Ziaco, Marcello, Dell’Isola, Mario, Affuso, Mario, Manzo, Emiliano, Nuzzo, Genoveffa, Fioretto, Laura, D’Ippolito, Giuliana, De Palma, Raffaele, Fontana, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972971/
https://www.ncbi.nlm.nih.gov/pubmed/36865548
http://dx.doi.org/10.3389/fimmu.2023.1050113