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Factors Influencing the Nitrogen-Source Dependent Flucytosine Resistance in Cryptococcus Species

Flucytosine (5-FC) is an antifungal agent commonly used for treatment of cryptococcosis and several other systemic mycoses. In fungi, cytosine permease and cytosine deaminase are known major players in flucytosine resistance by regulating uptake and deamination of 5-FC, respectively. Cryptococcus sp...

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Detalles Bibliográficos
Autores principales: Yang, Dong-Hoon, Khanal Lamichhane, Ami, Kwon-Chung, Kyung J., Chang, Yun C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973006/
https://www.ncbi.nlm.nih.gov/pubmed/36656038
http://dx.doi.org/10.1128/mbio.03451-22