Yersinia pestis Δail Mutants Are Not Susceptible to Human Complement Bactericidal Activity in the Flea

Ail confers serum resistance in humans and is a critical virulence factor of Y. pestis, the causative agent of plague. Here, the contribution of Ail for Y. pestis survival in the flea vector was examined. Rat or human but not mouse sera were bactericidal against a Y. pestis Δail mutant at 28°C in vi...

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Detalles Bibliográficos
Autores principales: Kolodziejek, Anna M., Bearden, Scott W., Maes, Sarah, Montenieri, John M., Gage, Kenneth L., Hovde, Carolyn J., Minnich, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973026/
https://www.ncbi.nlm.nih.gov/pubmed/36744930
http://dx.doi.org/10.1128/aem.01244-22