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SARS-CoV-2-Mediated Lung Edema and Replication Are Diminished by Cystic Fibrosis Transmembrane Conductance Regulator Modulators
Coronaviruses (CoVs) of genera α, β, γ, and δ encode proteins that have a PDZ-binding motif (PBM) consisting of the last four residues of the envelope (E) protein (PBM core). PBMs may bind over 400 cellular proteins containing PDZ domains (an acronym formed by the combination of the first letter of...
Autores principales: | Honrubia, Jose M., Gutierrez-Álvarez, Javier, Sanz-Bravo, Alejandro, González-Miranda, Ezequiel, Muñoz-Santos, Diego, Castaño-Rodriguez, Carlos, Wang, Li, Villarejo-Torres, Marta, Ripoll-Gómez, Jorge, Esteban, Ana, Fernandez-Delgado, Raul, Sánchez-Cordón, Pedro José, Oliveros, Juan Carlos, Perlman, Stanley, McCray, Paul B., Sola, Isabel, Enjuanes, Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973274/ https://www.ncbi.nlm.nih.gov/pubmed/36625656 http://dx.doi.org/10.1128/mbio.03136-22 |
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