Improved Dual Base Editor Systems (iACBEs) for Simultaneous Conversion of Adenine and Cytosine in the Bacterium Escherichia coli

Genome-editing (GE) techniques like base editing are ideal for introducing novel gain-of-function mutations and in situ protein evolution. Features of base editors (BEs) such as higher efficacy, relaxed protospacer adjacent motif (PAM), and a broader editing window enables diversification of user-de...

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Detalles Bibliográficos
Autores principales: Shelake, Rahul Mahadev, Pramanik, Dibyajyoti, Kim, Jae-Yean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973308/
https://www.ncbi.nlm.nih.gov/pubmed/36625577
http://dx.doi.org/10.1128/mbio.02296-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973308/
https://www.ncbi.nlm.nih.gov/pubmed/36625577
http://dx.doi.org/10.1128/mbio.02296-22

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