The IRE1α-XBP1 Signaling Axis Promotes Glycolytic Reprogramming in Response to Inflammatory Stimuli

Immune cells must be able to adjust their metabolic programs to effectively carry out their effector functions. Here, we show that the endoplasmic reticulum (ER) stress sensor Inositol-requiring enzyme 1 alpha (IRE1α) and its downstream transcription factor X box binding protein 1 (XBP1) enhance the...

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Detalles Bibliográficos
Autores principales: English, Bevin C., Savage, Hannah P., Mahan, Scott P., Diaz-Ochoa, Vladimir E., Young, Briana M., Abuaita, Basel H., Sule, Gautam, Knight, Jason S., O’Riordan, Mary X., Bäumler, Andreas J., Tsolis, Renée M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973330/
https://www.ncbi.nlm.nih.gov/pubmed/36475773
http://dx.doi.org/10.1128/mbio.03068-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973330/
https://www.ncbi.nlm.nih.gov/pubmed/36475773
http://dx.doi.org/10.1128/mbio.03068-22

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