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Identification of Gut Microbial Lysine and Histidine Degradation and CYP-Dependent Metabolites as Biomarkers of Fatty Liver Disease

Numerous studies have described specific metabolites as biomarkers of severe liver diseases, but very few have measured gut microbiota (GM)-produced metabolites in fatty liver disease. We aimed at finding GM signatures and metabolite markers in plasma and feces related to high liver fat content. Bas...

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Detalles Bibliográficos
Autores principales: Driuchina, Anastasiia, Hintikka, Jukka, Lehtonen, Marko, Keski-Rahkonen, Pekka, O’Connell, Thomas, Juvonen, Risto, Kuula, Juho, Hakkarainen, Antti, Laukkanen, Jari A., Mäkinen, Elina, Lensu, Sanna, Pietiläinen, Kirsi H., Pekkala, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973343/
https://www.ncbi.nlm.nih.gov/pubmed/36715540
http://dx.doi.org/10.1128/mbio.02663-22