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Endogenous Reverse Transcriptase Inhibition Attenuates TLR5-Mediated Inflammation

Transposable elements (TEs) are mobile genomic sequences that encompass roughly 50% of the human genome. Class 1 TEs, or “retrotransposons,” mobilize through the production of an RNA intermediate that is then reverse transcribed to form complementary DNA (cDNA) molecules capable of genomic reinserti...

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Detalles Bibliográficos
Autores principales: Dopkins, Nicholas, Singh, Bhavya, Michael, Stephanie, O’Mara, Morgan M., Marston, Jez L., Fei, Tongyi, Bendall, Matthew L., Nixon, Douglas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973353/
https://www.ncbi.nlm.nih.gov/pubmed/36645307
http://dx.doi.org/10.1128/mbio.03280-22