Cargando…

Endogenous Reverse Transcriptase Inhibition Attenuates TLR5-Mediated Inflammation

Transposable elements (TEs) are mobile genomic sequences that encompass roughly 50% of the human genome. Class 1 TEs, or “retrotransposons,” mobilize through the production of an RNA intermediate that is then reverse transcribed to form complementary DNA (cDNA) molecules capable of genomic reinserti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dopkins, Nicholas, Singh, Bhavya, Michael, Stephanie, O’Mara, Morgan M., Marston, Jez L., Fei, Tongyi, Bendall, Matthew L., Nixon, Douglas F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Observation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973353/ https://www.ncbi.nlm.nih.gov/pubmed/36645307 http://dx.doi.org/10.1128/mbio.03280-22

Ejemplares similares

Locus specific human endogenous retroviruses reveal new lymphoma subtypes
por: Singh, Bhavya, et al.
Publicado: (2023)

SARS-CoV-2 infection mediates differential expression of human endogenous retroviruses and long interspersed nuclear elements
por: Marston, Jez L., et al.
Publicado: (2021)

Cytosolic RNA:DNA Duplexes Generated by Endogenous Reverse Transcriptase Activity as Autonomous Inducers of Skin Inflammation in Psoriasis
por: Molès, Jean-Pierre, et al.
Publicado: (2017)

Human Endogenous Retrovirus K in Cancer: A Potential Biomarker and Immunotherapeutic Target
por: Curty, Gislaine, et al.
Publicado: (2020)

Specific human endogenous retroviruses predict metastatic potential in uveal melanoma
por: Bendall, Matthew L., et al.
Publicado: (2022)

Endogenous Plasmids and Chromosomal Genome Reduction in the Cardinium Endosymbiont of Dermatophagoides farinae
por: Xiong, Qing, et al.
Publicado: (2023)

Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells
por: Wu, Junyu, et al.
Publicado: (2021)

Nucleoside Analogue Reverse Transcriptase Inhibitors Differentially Inhibit Human LINE-1 Retrotransposition
por: Jones, R. Brad, et al.
Publicado: (2008)

Genome-wide identification of Reverse Transcriptase domains of recently inserted endogenous plant pararetrovirus (Caulimoviridae)
por: de Tomás, Carlos, et al.
Publicado: (2022)

A reverse transcriptase ribozyme
por: Samanta, Biswajit, et al.
Publicado: (2017)

Reverse transcriptase activity in psoriatic lesions: effects of reverse transcriptase inhibitors on keratinocyte proliferation and differentiation
por: Molès, Jean-Pierre, et al.
Publicado: (2009)

Involvement of Cisgender and Transgender Individuals in Studies on the Impact of Hormonal Therapy on COVID-19
por: Wozniak, Robert J., et al.
Publicado: (2020)

Human Endogenous Retrovirus Expression Is Upregulated in the Breast Cancer Microenvironment of HIV Infected Women: A Pilot Study
por: Curty, Gislaine, et al.
Publicado: (2020)

SARS-CoV-2 N Gene G29195T Point Mutation May Affect Diagnostic Reverse Transcription-PCR Detection
por: Ko, Karrie K. K., et al.
Publicado: (2022)

Attenuation of reverse transcriptase facilitates SAMHD1 restriction of HIV-1 in cycling cells
por: Tsai, Ming-Han C., et al.
Publicado: (2023)

The Membrane Composition Defines the Spatial Organization and Function of a Major Acinetobacter baumannii Drug Efflux System
por: Zang, Maoge, et al.
Publicado: (2021)

Low rates of nucleoside reverse transcriptase inhibitor and nonnucleoside reverse transcriptase inhibitor drug resistance in Botswana
por: Moyo, Sikhulile, et al.
Publicado: (2019)

Lack of Association between the Tlr4 (Lps(d)/Lps(d)) Genotype and Increased Susceptibility to Escherichia coli Bladder Infections in Female C3H/HeJ Mice
por: Suhs, Kaleigh A., et al.
Publicado: (2011)

Telomerase reverse transcriptase and neurodegenerative diseases
por: Yu, Xin, et al.
Publicado: (2023)

Reverse transcriptases prime DNA synthesis
por: Zabrady, Matej, et al.
Publicado: (2023)

2098: Endogenous reverse transcriptase (LINE-1) in human platelets regulates cell morphology and protein synthetic events
por: Schwertz, Hansjorg, et al.
Publicado: (2018)

Human Endogenous Retrovirus Expression Is Associated with Head and Neck Cancer and Differential Survival
por: Kolbe, Allison R., et al.
Publicado: (2020)

Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition
por: Dai, Lixin, et al.
Publicado: (2011)

Interconnections of Pseudomonas aeruginosa Quorum-Sensing Systems in Intestinal Permeability and Inflammation
por: Singh, Vijay K., et al.
Publicado: (2023)

APOBEC3 selects V179I in HIV-1 reverse transcriptase to provide selective advantage for non-nucleoside reverse transcriptase inhibitor-resistant mutants
por: Dwivedi, Richa, et al.
Publicado: (2022)

NMR characterization of HIV-1 reverse transcriptase binding to various non-nucleoside reverse transcriptase inhibitors with different activities
por: Thammaporn, Ratsupa, et al.
Publicado: (2015)

Genetic Evidence for Two Carbon Fixation Pathways (the Calvin-Benson-Bassham Cycle and the Reverse Tricarboxylic Acid Cycle) in Symbiotic and Free-Living Bacteria
por: Rubin-Blum, Maxim, et al.
Publicado: (2019)

Detection of Anaplasma phagocytophilum, Babesia microti, Borrelia burgdorferi, Borrelia miyamotoi, and Powassan Virus in Ticks by a Multiplex Real-Time Reverse Transcription-PCR Assay
por: Tokarz, Rafal, et al.
Publicado: (2017)

Reverse Transcriptase Activity in Mature Spermatozoa of Mouse
por: Giordano, Roberto, et al.
Publicado: (2000)

A diversity of uncharacterized reverse transcriptases in bacteria
por: Simon, Dawn M., et al.
Publicado: (2008)

Reverse transcriptases of retroviruses and retroelements: an evolutionary perspective
por: Arkhipova, Irina R
Publicado: (2009)

Telomerase reverse transcriptase in the regulation of gene expression
por: Zhou, Junzhi, et al.
Publicado: (2014)

Comprehensive Phylogenetic Analysis of Bacterial Reverse Transcriptases
por: Toro, Nicolás, et al.
Publicado: (2014)

Telomerase Reverse Transcriptase Regulates microRNAs
por: Lassmann, Timo, et al.
Publicado: (2015)

The mechano-chemistry of a monomeric reverse transcriptase
por: Malik, Omri, et al.
Publicado: (2017)

The Reverse Transcriptases Associated with CRISPR-Cas Systems
por: Toro, Nicolás, et al.
Publicado: (2017)

Implications of telomerase reverse transcriptase in tumor metastasis
por: Zou, Yongkang, et al.
Publicado: (2020)

Quantitative Reverse Transcriptase Polymerase Chain Reaction
por: Gommersall, Lyndon M., et al.
Publicado: (2007)

50th anniversary of the discovery of reverse transcriptase
por: Coffin, John M.
Publicado: (2021)

Competing endogenous RNA network in newly diagnosed multiple myeloma by genetic microarray
por: He, Yu-Qin, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fi2rck7c4ni0fti11cogike4f1