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Multiple Sites on Glycoprotein H (gH) Functionally Interact with the gB Fusion Protein to Promote Fusion during Herpes Simplex Virus (HSV) Entry

Enveloped virus entry requires fusion of the viral envelope with a host cell membrane. Herpes simplex virus 1 (HSV-1) entry is mediated by a set of glycoproteins that interact to trigger the viral fusion protein glycoprotein B (gB). In the current model, receptor-binding by gD signals a gH/gL hetero...

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Detalles Bibliográficos
Autores principales: Fan, Qing, Hippler, Daniel P., Yang, Yueqi, Longnecker, Richard, Connolly, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973363/
https://www.ncbi.nlm.nih.gov/pubmed/36629412
http://dx.doi.org/10.1128/mbio.03368-22