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Oxoeicosanoid signaling mediates early antimicrobial defense in zebrafish

5-oxoETE is a bioactive lipid derived from arachidonic acid generated when phospholipase A(2) activation coincides with oxidative stress. Through its G protein-coupled receptor OXER1, pure 5-oxoETE is a potent leukocyte chemoattractant. Yet, its physiological function has remained elusive owing to t...

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Detalles Bibliográficos
Autores principales: Ma, Yanan, Hui, King Lam, Gelashvili, Zaza, Niethammer, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973399/
https://www.ncbi.nlm.nih.gov/pubmed/36640321
http://dx.doi.org/10.1016/j.celrep.2022.111974