The ADAM17-directed Inhibitory Antibody MEDI3622 Antagonizes Radiotherapy-induced VEGF Release and Sensitizes Non–Small Cell Lung Cancer for Radiotherapy

The cellular response to ionizing radiation (IR) depends on tumor cell and microenvironmental factors. Here, we investigated the role of IR-induced ADAM17 matrix metalloproteinase activity for the intercellular communication between tumor cells and the tumor vasculature in non–small cell lung cancer...

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Detalles Bibliográficos
Autores principales: Tschanz, Fabienne, Bender, Sabine, Telarovic, Irma, Waller, Verena, Speck, Roberto F., Pruschy, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973400/
https://www.ncbi.nlm.nih.gov/pubmed/36860547
http://dx.doi.org/10.1158/2767-9764.CRC-21-0067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973400/
https://www.ncbi.nlm.nih.gov/pubmed/36860547
http://dx.doi.org/10.1158/2767-9764.CRC-21-0067

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