Targeting NEDDylation is a Novel Strategy to Attenuate Cisplatin-induced Nephrotoxicity

Although cisplatin remains a backbone of standard-of-care chemotherapy regimens for a variety of malignancies, its use is often associated with severe dose-limiting toxicities (DLT). Notably, 30%–40% of patients treated with cisplatin-based regimens are forced to discontinue treatment after experien...

Descripción completa

Detalles Bibliográficos
Autores principales: Jones, Trace M., Espitia, Claudia M., Chipollini, Juan, Lee, Benjamin R., Wertheim, Jason A., Carew, Jennifer S., Nawrocki, Steffan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973416/
https://www.ncbi.nlm.nih.gov/pubmed/36860653
http://dx.doi.org/10.1158/2767-9764.CRC-22-0340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973416/
https://www.ncbi.nlm.nih.gov/pubmed/36860653
http://dx.doi.org/10.1158/2767-9764.CRC-22-0340

Ejemplares similares