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Humanized Patient-derived Xenograft Models of Disseminated Ovarian Cancer Recapitulate Key Aspects of the Tumor Immune Environment within the Peritoneal Cavity

The importance of the immune microenvironment in ovarian cancer progression, metastasis, and response to therapies has become increasingly clear, especially with the new emphasis on immunotherapies. To leverage the power of patient-derived xenograft (PDX) models within a humanized immune microenviro...

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Detalles Bibliográficos
Autores principales: Steinkamp, Mara P., Lagutina, Irina, Brayer, Kathryn J., Schultz, Fred, Burke, Danielle, Pankratz, Vernon S., Adams, Sarah F., Hudson, Laurie G., Ness, Scott A., Wandinger-Ness, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973420/
https://www.ncbi.nlm.nih.gov/pubmed/36860657
http://dx.doi.org/10.1158/2767-9764.CRC-22-0300